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They are sometimes called neurokinin-1 receptor antagonists. Aprepitant and fosaprepitant - these are newer medicines and work by blocking a chemical that acts on neurokinin receptors in the body to cause nausea.These medicines are useful for controlling nausea and vomiting caused by chemotherapy. Serotonin (5-HT) has an action in the gut and the brain to cause nausea. Granisetron, ondansetron, and palonosetron - these medicines work by blocking a chemical called serotonin (5-HT) in the gut, and the brain.The reason why it reduces nausea is not clear. Dexamethasone has a wide range of actions on many parts of the body. It is a man-made version of a natural hormone produced by your own body. Dexamethasone - this is a steroid medicine.It is not usually used for more than a few days. (CTZ stands for chemoreceptor trigger zone.) It also speeds up the emptying of the gut. Domperidone- this medicine works on the CTZ.It is often used for people with sickness due to gut problems or migraine. It eases the feelings of sickness by helping to empty the stomach and speed up how quickly food moves through the gut. Metoclopramide - this medicine works directly on your gut.It works for many common causes of nausea, including vertigo, ear problems and sickness in pregnancy. Prochlorperazine (or brand name Stemetil®) is one of the most used medicines for nausea. They are useful for nausea that is caused by some cancers, radiation and opiate medicines such as morphine and codeine. Chlorpromazine, haloperidol, perphenazine, prochlorperazine, levomepromazine - these medicines work by blocking a chemical in the brain called dopamine.It works well for nausea caused by ear problems and motion sickness. It is a type of medicine called an antimuscarinic (or anticholinergic). Hyoscine - this medicine works by blocking a chemical in the brain called acetylcholine.They are thought to work well for nausea caused by a number of conditions including ear problems and motion (travel) sickness. It is thought that antihistamines block histamine 1 (H1) receptors in the area of the brain which creates nausea in response to chemicals in the body. The exact way that they work is not fully understood. Cinnarizine, cyclizine, promethazine - these medicines belong to a group of medicines called antihistamines.Listed below are some of the more commonly prescribed medicines:
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Other medicines work on the brain and block signals to the vomiting centre. Some of these medicines work on the gut and speed up how quickly food moves through it. The medicines for nausea used are sometimes called antiemetics. What are medicines for nausea and how do they work?